|Statement||by Amand Routh|
|Contributions||Medical Society of London, Royal College of Surgeons of England|
|The Physical Object|
|Pagination||12 p. :|
|Number of Pages||12|
SPORADIC CRETINISM is not only interesting from its rarity, but has acquired an unusually high degree of importance of late from its probable affinity to myxoedema in adults. The following account of five cases I have lately met with, of which two are represented by woodcuts, will Author: Robert Kirk. The result is Myxoedema of Cretinism, the first being a disease of advanced life, the second of early years. Cretinism may be congenital, the gland being absent. More commonly it atrophies after one of the fevers. Where goitre (q.v.) is epidemic, cretinism occurs; the gland is enlarged in these cases. A LARGE number of cases of myxoedema and several sporadic cretins are being treated at the present time by thyroid juice in one form or another, so that a few observa- tions which have been made during the last two years in the course of treating eight cases of myxoedema may be of by: 1. After being put on thyroid extract the menstruation ceased. Byrom Bramwell reported a case of sporadic cretinism without amenorrhcea in THE LANCET. A patient, aged 36 years, whose height was 36 inches, with all the signs of cretinism, had menstruated regularly after the age of Her intellectual development was that of a child of 5 or 6 years.
The Lancet ON FIVE CASES OF SPORADIC CRETINISM IN SCOTLAND. Robert Kirk M.D., F.F.P.S. GLASG OUT-DOOR PHYSICIAN-ACCOUCHEUR TO THE GLASGOW WESTERN INFIRMARY. (Concluded from page ) CASE J. R-, male, aged thirty years, born at Fal. kirk, where he still lives. Cretinism is of 2 types: Congenital Cretinism. Incidence is to in an iodine-deficient endemic area. It can be caused due to a defect in the genes encoding various enzymes involved in thyroid hormone synthesis such as thyroglobulin, iodotyrosine . Start studying Endocrine pathology: Hypothyroidism, cretinism, myxedema, and thyroditis. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Acromegaly, giantism, and dwarfism are the result of overproduction or underproduction of growth horomones by the pituitary gland. Cretinism/myxedema are hypothyroid conditions that result from insufficeint quantities of thyroid hormones produced by the thyroid gland. Both are disorders of the endocrine system that can result in deforimities.
' The favorable reports from cases of sporadic cretinism treated with the -hyroid extract encouraged us to try it in this case, and the child has been ;aking the glycerin extract of the sheep’s thyroid in an amount corresponding ix) about a quarter of a gland in the twenty-four hours. About this Item: pamphlet. 1 page (p. ) IN: The British Medical Journal, , vol. 2, Dec 1st. 4to, modern wrappers. London, First Edition. Whole issue offered entire. Semon argued that cachexia strumipriva, myxoedema, and cretinism were all due to loss of function of the thyroid. cretinism is the product of generations of goitrous families. The cause of sporadic cretinism is less definite. Affected children are the offspring of healthy parents. The mother in some cases may have a small goitre, but signs of myxoedema are not present. In sporadic cases it is probable that there is a developmental defect. Congenital hypothyroidism, previously known as cretinism, is a severe deficiency of thyroid hormone in newborns. It causes impaired neurological .